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Investigation Reveals More Woes for Rosiglitazone 5 Sep 2010

On July 15 (MedPage Today) -- a day after the FDA completed two days of hearings on rosiglitazone (Avandia) -- a British advisory commission on drugs concluded that the product should be withdrawn from the market, according to an investigation conducted by BMJ.

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ESC: Stockholm Take Home Message -- Watch the 'Not' Warfarins 3 Sep 2010

STOCKHOLM (MedPage Today) -- An investigational antiplatelet -- ticagrelor (Brilinta) -- emerged as a big winner from the five-day long European Society of Cardiology congress, but the buzz here focused instead on a trio of investigational oral anticoagulants -- dabigatran, rivaroxaban, and apixaban.

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Increased Cardiac Events Seen With Sibutramine (CME/CE) 2 Sep 2010

(MedPage Today) -- Overweight patients with cardiovascular risks who took the weight-loss drug sibutramine had an increased likelihood of experiencing a cardiac event, a large randomized trial found.

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Tight BP Control Flops for Most CKD Patients (CME/CE, with audio) 1 Sep 2010

(MedPage Today) -- Intensive blood pressure control doesn't slow progression of chronic kidney disease (CKD) in hypertensive patients overall but may help those with baseline proteinuria, according to a randomized trial.

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ESC: New Anticoagulants Create Buzz 1 Sep 2010

STOCKHOLM (MedPage Today) -- After years of waiting for an alternative to warfarin (Coumadin), there are now three wending their way through the regulatory process. In this exclusive InFocus video report we review each of these new agents with leading cardiologists.

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ESC: EINSTEIN DVT Data Positive for Factor Xa Inhibitor (CME/CE) 31 Aug 2010

STOCKHOLM (MedPage Today) -- An investigational oral anticoagulant appears to be as effective and safe as treatment with enoxaparin (Lovenox) plus warfarin (Coumadin) to prevent recurrent deep vein thrombosis, researchers reported.

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ESC: It's Not Butter and It's Not Better (CME/CE, with video) 29 Aug 2010

STOCKHOLM (MedPage Today) -- Adding margarine enriched with omega-3 fatty acids as a dietary intervention did not prevent second heart attacks in older men and women at risk for worsening heart disease, researchers said here.

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Novel Combo Pill for Hypertension Approved 27 Aug 2010

(MedPage Today) -- Another type of combination pill for hypertension has won FDA approval -- this time putting a direct renin inhibitor together with a calcium channel blocker.

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Diabetes, Insulin Resistance Linked to Alzheimer's (CME/CE) 27 Aug 2010

(MedPage Today) -- Insulin resistance and type 2 diabetes may contribute to the development of one type of brain plaque linked to Alzheimer's disease, according to an autopsy study.

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Hb Variability Doesn't Predict Mortality in Dialysis (CME/CE) 27 Aug 2010

(MedPage Today) -- Variability in blood hemoglobin levels, associated with the use of erythropoiesis-stimulating agents (ESAs), does not predict mortality in dialysis patients, according to a large European population study.

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One TZD No Safer than Another (CME/CE) 25 Aug 2010

(MedPage Today) -- The diabetes drug pioglitazone (Actos) carries cardiac risk similar to that found for embattled sister compound rosiglitazone (Avandia), according to an analysis of an administrative claims database.

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ESC: Daily Coffee Limbers Up the Heart (CME/CE) 25 Aug 2010

STOCKHOLM (MedPage Today) -- A daily coffee habit may counteract aortic stiffness in older adults with hypertension, researchers reported.

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Migraine Raises Long-Term CV Risks (CME/CE) 24 Aug 2010

(MedPage Today) -- Patients who have migraine headaches face heightened long-term risks of cardiovascular disease and death, according to analyses of outcomes from two large cohort studies.

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Gene Variants May Predict ESRD in Diabetics (CME/CE) 24 Aug 2010

(MedPage Today) -- Polymorphisms in the gene for protein kinase C-β were strongly predictive of end-stage renal disease (ESRD) in Chinese patients with type 2 diabetes, according to researchers in Hong Kong.

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Green Veggies Cut Diabetes Risk (CME/CE) 19 Aug 2010

(MedPage Today) -- Increasing the daily intake of green leafy vegetables could significantly reduce the risk of type 2 diabetes, a British meta-analysis found.

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