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How Bone-Marrow Stem Cells Hold Their 'Breath' In Low-Oxygen Environments 6 Sep 2010

UT Southwestern Medical Center researchers have identified unique metabolic properties that allow a specific type of stem cell in the body to survive and replicate in low-oxygen environments...

HeartWare Receives Second Patient Allotment Under Continued Access Protocol For Pivotal U.S. Bridge-To-Transplant Clinical Trial 4 Sep 2010

HeartWare International, Inc. (Nasdaq: HTWR; ASX: HIN), a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced that the U.S...

New Warning Signs May Predict Kidney Transplant Failure 3 Sep 2010

Kidney transplants that show a combination of fibrosis (scarring) and inflammation after one year are at higher risk of long-term transplant failure, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN)...

New Research Demonstrates Safety Of Cord-blood-derived Stem Cell Treatments 3 Sep 2010

In a new peer-reviewed article published by the Journal of Translational Medicine, scientists from Beike Biotechnology, China's leading stem cell research and regenerative medicine company, and Medistem, Inc...

Occurrence Of Increased Kidney Transplant Listings In Patients With Prior Non-Kidney Transplants 3 Sep 2010

Individuals who received a non-kidney organ transplant in the past may be more likely to be listed for a kidney transplant prior to initiation of dialysis (pre-emptive listing) than other candidates, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN)...

Beaumont Hospitals Launches New Liver Transplant Program 2 Sep 2010

Beaumont Hospital, Royal Oak became Michigan's third liver transplant center on Aug. 31. A 59-year-old man from Royal Oak was the first patient to receive a liver transplant through Beaumont's new multi-organ transplant program. Under the leadership of Alan J. Koffron, M.D...

Vitrolife: New Study Shows Improved Survival With Perfadex 1 Sep 2010

A recently published study in The Journal of Heart and Lung Transplantation shows that the patients who are most seriously ill before lung tranplantation have better one-year survival when Perfadex is used as the preservation solution for donor lungs compared with UW solution...

Eyegenix™ Artificial Cornea Achieves Major Advancement Towards Curing Corneal Blindness 1 Sep 2010

Eyegenix™, the ophthalmic division of Cellular Bioengineering, Inc. (CBI), announced that the results of a pilot clinical trial using a synthetic cornea for which Eyegenix™ holds the exclusive global license for transplantation were published in the peer-reviewed journal, Science Translational Medicine (Volume 2, Issue 46, August, 25, 2010)...

Launch Of New Cell Transplantation Journal 31 Aug 2010

A new and unique journal on cell transplantation aimed at helping translate laboratory findings into clinical applications is being launched by Cognizant Communication Corporation as a companion journal to Cell Transplantation. Cell Medicine, an online-only, open access journal, publishes research papers that promise to have direct clinical relevance. The journal is freely accessible here...

Bone Marrow From An Aboriginal Canadian May Be Best Match For Baby With Rare Genetic Disorder 31 Aug 2010

Bone marrow from a matched Aboriginal Canadian donor may be the best chance Harold and Lindsey Bost's daughter, Leona, has for survival. The five-month-old was born with Cartilage-Hair Hypoplasia (CHH). CHH is a rare genetic disorder characterised by short stature, fine, sparse hair, and immunodeficiency requiring bone marrow or stem cell transplantation...

Biosynthetic Corneas Restore Sight In Patients With Significant Vision Loss 26 Aug 2010

Patients with corneal damage and considerable vision loss had biosynthetic corneas implanted into their eyes with FibroGen's proprietary rhCIII (recombinant human type III collagen), which restored their vision and promoted nerve regeneration. A report on this 2-year Phase I clinical trial has been published in the peer-reviewed journal Science Translational Medicine...

3SBio And Isotechnika Pharma Announce Strategic Partnership To Develop And Commercialize Voclosporin In China 25 Aug 2010

3SBio Inc. ("3SBio") (Nasdaq: SSRX), a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products and Isotechnika Pharma Inc...

Heart Transplant Patients With Common Disorder Have High Survival Rates 25 Aug 2010

Transplant surgery to correct the most common type of genetic heart disease yields similar short-term and potentially greater long-term survival rates as transplant surgery for other heart diseases, according to research reported in Circulation: Heart Failure, an American Heart Association journal...

EHSI: New Stem-Cell Study An 'Encouraging Step' Towards Organ Regeneration 25 Aug 2010

Cindy Morrissey, President and CEO of Emerging Healthcare Solutions, Inc., called the results of a recent study on Friday an 'encouraging step' towards the use of stem cells to regenerate human organs. The research, published in the journal Nature, shows that it is possible to convert one stem cell type to another, without the need for genetic modification...

Extensive Trial Confirms Benefits Of Early Steroid Withdrawal For Transplant Patients 25 Aug 2010

A University of Cincinnati (UC) analysis of 10 years of data from local kidney transplant patients shows that patients removed from a corticosteroid regimen shortly after surgery have better graft survival rates, better survival rates and fewer cardiovascular events than patients kept on the traditional regimen of long-term steroids...

Soligenix Announces Award Of $1.2 Million FDA Orphan Products Development Grant 24 Aug 2010

Soligenix, Inc. (OTC Bulletin Board: SNGX) (Soligenix or the Company), a late-stage biopharmaceutical company, announced that it has been awarded a three year $1.2 million clinical research grant by the Office of Orphan Products Development (OOPD) of the U.S. Food and Drug Administration (FDA) pursuant to its Orphan Products Development (OPD) Program...

Report Describes How Alonzo Mourning Uses His NBA Fame To Fight Kidney Disease 21 Aug 2010

In October 2000, Mourning was diagnosed with focal segmental glomerular sclerosis (FSGS), a kidney disease that causes scarring in the glomeruli, the blood vessels in the kidneys that filter the blood to make urine. Mourning was obviously unsettled by this news in the midst of a Hall of Fame caliber NBA career. "I was devastated, scared, and unsure about my future... looking for answers...

Frozen Flies May Yield Secrets For Human Organ Transplants 21 Aug 2010

When kitchens become infiltrated with fruit flies, especially during the dog days of summer, homeowners might wish that the flying pests would just turn to ice. The fruit fly Drosophila melanogaster does boast a powerful genetic system making it an ideal organism to test a cool new discovery: how an enzyme regulates body energy levels...

Hispanics And Asians Less Likely To Receive Liver Transplants 20 Aug 2010

Researchers at the University of Michigan and Arbor Research Collaborative for Health, both in Ann Arbor, have identified geographic variation as a key factor accounting for disparities in access to liver transplantation among racial and ethnic groups...

Health Disparities Exist Among Black And Hispanic Kidney Donors 20 Aug 2010

Black and Hispanic kidney donors are significantly more likely than white donors to develop hypertension, diabetes and chronic kidney disease, according to new Saint Louis University research published in the August 19, 2010 issue of the New England Journal of Medicine. "We've long known that diabetes and hypertension disproportionately affect blacks and Hispanics...

Identifying Factors Which Predict Alcohol Use After Liver Transplantation 20 Aug 2010

Patients who receive a liver transplant due to alcoholic liver disease need to demonstrate periods of abstinence and often attend addiction treatment before transplantation. However, alcohol use disorders can recur, as can other diseases requiring transplantation, and thus alcohol use after liver transplantation is not uncommon...

NHSBT Annual Review 2009/2010 - Saving And Improving Lives 19 Aug 2010

A major improvement programme around the production of lifesaving blood delivered savings for the NHS of Â£20 million last year according to NHS Blood and Transplant (NHSBT) whose Annual Review 2009-10 was published yesterday. Improvements in manufacturing and processing enabled blood to be produced more efficiently leading to a reduction in price per unit from Â£140 to Â£130...

NHSBT Response To Lancet Article On Success Of Donation After Cardiac Death Kidney Transplants 19 Aug 2010

NHSBT welcomes this study which highlights the success of kidney transplants made possible through donors who have died from "cardiac death". Donation after cardiac death (DCD) has been increasing steadily in the UK for some years. NHSBT has invested in several schemes in the wider NHS in order to help facilitate this type of donation...

Chronic Health Conditions Common For Stem Cell Transplant Survivors 19 Aug 2010

Although hematopoietic cell transplantation (HCT) cures many blood diseases, two-thirds of long-term survivors report at least one chronic health condition after the procedure, according to a recent study published online in Blood, the journal of the American Society of Hematology...

Quark Pharmaceuticals And Major Pharmaceutical Company Enter Into Licensing Option Agreement For The P53 Suppressor Drug QPI-1002 19 Aug 2010

Quark Pharmaceuticals, Inc., a world leader in the discovery and development of RNAi-based therapeutics, announced that it has granted Novartis an option to obtain an exclusive worldwide license to develop and commercialize its p53 temporary inhibitor siRNA drug QPI-1002, currently the subject of a Phase II clinical trial. Quark will receive initially a non-refundable fee of 10 million USD...

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