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UC San Diego To Lead New Pharmacogenomics Project 8 Sep 2010

An international team, led by University of California, San Diego School of Medicine researchers, has been awarded a $6.5 million grant from the National Institutes of Health (NIH) to study the pharmacogenomics of a key mood-stabilizing drug used to treat bipolar disorder...

NIH Awards Nearly $10 Million To UF Pharmacogenomics Researcher 8 Sep 2010

A University of Florida genetics researcher has received $9.8 million to further a national effort to use genetic data to more effectively pinpoint which medications and treatments are best for individual patients. Julie A. Johnson, Pharm.D...

Consumers Have Concerns About Home Genetic Tests 8 Sep 2010

One-half of people using direct-to-consumer (DTC) personal genetic risk tests express concerns about testing-yet more than 80 percent want to know their risk even for non-preventable genetic diseases, according to a study in the September Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics (ACMG)...

Explaining An Important Genetic Cardiovascular Risk Factor 8 Sep 2010

New findings reported in the September issue of Cell Metabolism, a Cell Press publication, appear to explain why people who carry specific and common versions of a single gene are more likely to have high cholesterol and to suffer a heart attack. Studies in mice show that the gene, known as sortilin (SORT1), controls the release of LDL (a.k.a...

To Reach, Perchance To Kill The Cancer: A Soliloquy From Epeius Nanotechnologies Opposes That 'Sea Of Troubles' 8 Sep 2010

Epeius Biotechnologies Corporation, a leader in the emerging field of targeted genetic medicine, reports the publication of a landmark paper in clinical oncology. Following up on its advanced U.S...

St. Jude Researcher Receives Grant To Focus On Cancer Pharmacogenomics In Children 8 Sep 2010

With its new expansion of the Pharmacogenomics Research Network (PGRN), the National Institutes of Health (NIH) awarded St. Jude Children's Research Hospital a prestigious grant to focus on anticancer agent research in children. The five-year, $8.6 million grant is titled "PAAR4Kids Pharmacogenomics of Anticancer Agents Research in Children." "We've been part of the PGRN for 10 years...

Sequencing Of First Irish Genome 8 Sep 2010

The first entire genome of an Irish individual has been sequenced. The sequence is reported in BioMed Central's open access journal, Genome Biology and provides insight into the evolutionary history of this distinct lineage...

Scientists Create New Process To 'Program' Cancer Cell Death 8 Sep 2010

Researchers at the California Institute of Technology (Caltech) have engineered a fundamentally new approach to killing cancer cells...

Universal Screening Of Newborns For Congenital Adrenal Hyperplasia Recommended 7 Sep 2010

Today, The Endocrine Society released a new clinical practice guideline on the diagnosis and treatment of congenital adrenal hyperplasia (CAH). The guideline features a series of evidence-based clinical recommendations developed by an expert task force...

Epitwin: Largest Ever Epigenetics Project Launched 7 Sep 2010

One of the most ambitious large-scale projects in Human Genetics has been launched: Epitwin will capture the subtle epigenetic signatures that mark the differences between 5,000 twins on a scale and depth never before attempted, providing key therapeutic targets for the development of drug treatments...

The Role Of CEP290 In Maintaining Ciliary Function Defined By Researchers 7 Sep 2010

A new study in the September 6 issue of the Journal of Cell Biology helps define the role of an important ciliary protein, CEP290. The results could be applied toward targeted gene therapy in cilia-related diseases. Mutations in human CEP290 cause cilia-related disorders that range in severity from isolated blindness to perinatal death...

New Treatment Activates Death Program In Cancer Cells 7 Sep 2010

Cancer is a difficult disease to treat because it's a personal disease. Each case is unique and based on a combination of environmental and genetic factors. Conventional chemotherapy employs treatment with one or more drugs, assuming that these medicines are able to both "diagnose" and "treat" the affected cells...

CGC Genetics Introduces MicroArray Panel For Molecular Diagnosis Of Thrombophilia And Warfarin Pharmacogenetics 7 Sep 2010

CGC Genetics, a 18 year-old European medical genetic testing company has recently expanded to the USA. The company offers a broad menu of more than 1,500 molecular diagnostic, cytogenetic and clinical genomic CLIA laboratory tests that cover all the major disciplines of medicine...

DNA Fingerprinting Pioneer Discovers Role Of Key Genetic Catalyst For Human Diversity 6 Sep 2010

Research by DNA fingerprinting pioneer and his team at University of Leicester defines engine for change in genetic hotspots...

Reducing Stem Cell Loss During Cancer Treatment 6 Sep 2010

Biologists at the University of California, San Diego have discovered that a gene critical for programmed cell death is also important in the loss of adult stem cells, a finding that could help to improve the health and well-being of patients undergoing cancer treatment...

Research By DNA Fingerprinting Pioneer And His Team At University Of Leicester Defines Engine For Change In Genetic Hotspots 6 Sep 2010

One of the key drivers of human evolution and diversity, accounting for changes that occur between different generations of people, is explained by new research published by world-renowned scientist Professor Sir Alec Jeffreys, who discovered DNA fingerprinting at the University of Leicester...

New Animal Model For Hemophilia A Developed By Yale 6 Sep 2010

Researchers at Yale School of Medicine have developed a new animal model for studying hemophilia A, with the goal of eventually treating people with the disorder. Hemophilia A, a hereditary defect that prevents blood from clotting normally, is caused by a variety of mutations in the factor VIII gene...

Induced Pluripotent Stem Cell Retain An Inactivated X Chromosome 6 Sep 2010

Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at UCLA have found. The finding could have implications for studying X chromosome-linked diseases such as Rett syndrome, caused by mutations in a gene located on the X chromosome...

Lineagen, Inc. Selected To Present At The 2010 Genetic Risk Factors For Autism: Translating Discoveries Into Diagnostics Symposium In Toronto 5 Sep 2010

Lineagen, Inc., a developer of innovative genomic tests and services for the screening, evaluation and diagnosis of complex disorders and diseases including autism spectrum disorders, announced today that Dr. Michael S...

Dr Manuel Ferreira Is A QIMR Geneticist On A Mission To Discover The Underlying Causes Of Asthma, Australia 5 Sep 2010

He is heading the largest Australian study of asthma genetics - the Australian Asthma Genetics Consortium - which has brought together the top asthma genetics experts from across the country to try to solve the genetic puzzle of asthma. For 1 in 10 Australians, asthma is part of their everyday life...

Low Grades In Adolescence Linked To Dopamine Genes 5 Sep 2010

The academic performance of adolescents will suffer in at least one of four key subjects - English, math, science, history - if their DNA contains one or more of three specific dopamine gene variations, according to a study led by renowned biosocial criminologist Kevin M. Beaver of The Florida State University...

Genetically Modified Salmon As Safe To Eat As Normal Atlantic Salmon 4 Sep 2010

U.S. regulators say that genetically engineered salmon as safe to eat as wild Atlantic salmon, after completing a preliminary analysis. Aqua Bounty Technologies Inc., have genetically modified their salmon so that they eat all year round and grow twice as fast as salmon typically would in their natural environments. Genetically modified (engineered) salmon is an Atlantic salmon...

Peeling Back DNA Packaging To Gain Insight Into Cells 4 Sep 2010

Scientists have built a clearer picture of how lengthy strands of DNA are concertinaed when our cells grow and divide, in a discovery could help explain how cell renewal can go wrong. Scientists have identified thousands of proteins that play a key role in compacting DNA - a crucial process by which DNA is shortened up to 10,000 times to fit inside cells as they split into two...

Lupus Research Institute-Funded Study Points To Increased Risk For Lupus In Men 4 Sep 2010

Lupus Research Institute-funded researcher Betty Tsao, PhD, at the University of California Los Angeles has discovered that humans - males in particular - with a variant form of the immune receptor gene "Toll Like Receptor 7 (TLR7)" are at increased risk of developing the autoimmune disease systemic lupus erythematosus (lupus)...

The Art Of Dividing 4 Sep 2010

A basic requirement for growth and life of a multicellular organism is the ability of its cells to divide. Chromosomes in the cells duplicate and are then distributed among the daughter cells. This distribution is organized by a protein complex made up of several hundred different proteins, called the centrosome...

Genetics News From Medical News Today